During cell division, the equal segregation of the replicated genome to daughter cells requires a microtubule-based bipolar spindle. The spindle is a dynamic self-organizing structure, with ...

Each of us has enough DNA to reach from here to the sun and back, more than 300 times. How is all of that DNA packaged so tightly into chromosomes and squeezed into a tiny nucleus? Long, slender DNA ...

The meeting will encompass a structural perspective of chromatin, highlighting developments in our understanding of its organization and the impact on biological functions such as DNA replication, ...

If stretched out and laid end-to-end, the DNA in a human cell's 46 chromosomes would span about 6 feet. Yet it fits inside of a nucleus only micrometers in diameter. Somehow, the DNA gets compacted by ...

Human life hinges on the ability of our cells to cram six feet of DNA into a 10-micron nucleus—equivalent to fitting a mile of string inside one green pea. But stuffing genes into cramped quarters is ...