In a recent study, researchers manipulated cellular proteins that control genes in aged mice. Experimental results showed their livers were rejuvenated to younger states. This work shows promise as a ...

CRISPR-Cas9 has been widely adapted for use in transcriptional modulation and epigenetic engineering with deactivated Cas9 (dCas9) systems to enable CRISPR interference (CRISPRi) and CRISPR activation ...

Revvity's Dharmacon All-in-one lentiviral platform has expanded to include whole-genome library options for CRISPR knockout (CRISPRko), CRISPR interference (CRISPRi), and CRISPR activation (CRISPRa).

Researchers at Texas A&M are pairing a widely used ingredient with advanced medical technology to develop new treatments for ...

Study identifies a new set of genes and cellular pathway that play a role in the risk of developing Parkinson’s disease Scientists searched the entire human genome using CRISPR interference technology ...

UC and Broad have been involved in two interferences at the patent office. Interference No. 106,115 was the second interference between UC and Broad over patent rights to CRISPR-Cas9 technology in ...

An international multidisciplinary team has demonstrated for the first time that CRISPR-based gene activation (CRISPRa) can be used to treat genetic heart disease in vivo. The study, published in the ...

Brendan Jones Ph.D., Xianfeng Morgan Xu, Ph.D. The past week was a truly remarkable week for the CRISPR gene editing field. New developments have reshaped both the legal and scientific landscapes for ...

Kampmann’s work, supported by the National Institutes of Health (NIH), maps cellular “decision points” that determine whether brain cells survive or die — laying the groundwork for treatments that ...

Editas Medicine Announces U.S. Court of Appeals for the Federal Circuit Remands CRISPR Patent Interference to Patent Trial and Appeal Board Editas Medicine Announces U.S. Court of Appeals for the ...