Blood is an ideal, minimally invasive sample for biomarker discovery, but its complexity might make untargeted, deep proteomics challenging. This work compares plasma proteomics approaches using both ...

Relationship between immune-inflammatory markers and clinical features and deepness of tumor response and prognosis of patients with PD-L1 ≥50% metastatic NSCLC receiving first-line immunotherapy.

A new HIC–MS method using ammonium tartrate improves ADC characterization, enabling efficient drug-to-antibody ratio analysis without complex workflows. A proteomics workflow combining laser ablation ...

Protein biomarker discovery, validation and utilization require technologies that deliver proteome insights with breadth and depth. Liquid chromatography mass spectrometry (LC-MS), the gold-standard ...

MOBILion Systems demonstrated that high-resolution ion mobility in its PAMAF mode overcame LC-MS inefficiencies, enabling ...

In mass spectrometry (MS), workflows are being streamlined and analyses are becoming more sophisticated. In short, MS is becoming faster, easier to use, and more functional. This is welcome news for ...

In living organisms, protein molecules with different chemical structures called proteoforms, are produced from a single gene to perform a variety of physiological protein functions. It has been known ...

To identify specific chemicals or molecules in the life sciences and medical research, scientists often use mass spectrometry (MS), usually paired with liquid chromatography (LC). These technologies ...

The proteomics market is experiencing strong growth as demand rises for advanced tools that analyze protein structure, ...