During translation, multiple ribosomes travel along the nucleic acid chain to build polypeptides that become functional proteins. Occasionally, these molecular decoders pause on the mRNA, either ...

The genetic information stored in DNA is a living archive of instructions that cells use to accomplish the functions of life. Inside each cell, catalysts seek out the appropriate information from this ...

Mitochondrial ribosomes, or mitoribosomes, are specialised organellar complexes responsible for synthesising a subset of proteins encoded by mitochondrial DNA. These proteins are critical for the ...

These spots are socRNAs being translated by ribosomes in a cell. They get brighter over time, showing active translation. The complex, which includes the socRNA and ribosome, is attached to the plasma ...

Slower ribosomes stall during translation and collide with faster ones, triggering selective degradation of their small subunits. This “ribosome competition” mechanism ensures that only efficient ...

Maximiliane Wieland, Mikael Holm, Emily J. Rundlet, Martino Morici, Timm O. Koller, Tinashe P. Maviza, Domen Pogorevc, Ilya A. Osterman, Rolf Müller, Scott C ...

Ribosomes are molecular machines that translate messenger RNA (mRNA), which is transcribed from DNA, into proteins. Scientists have now learned more about ribosomes in nature, and their function. This ...

Vaccinations have revolutionized healthcare, but designing them remains complex, requiring time and creativity, especially for vaccines against viruses, which are difficult to study. “Each virus ...

Defects in ribosome biogenesis, assembly, and function of individual ribosomes are termed ribosomopathies. They are characterized by tissue-specific phenotypic abnormalities that consequently increase ...

A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency partially depends on the usage of a codon, or sequence of three nucleotides, that ...